O. N. Zefirova, E. V. Nurieva, H. Lemcke, A. A. Ivanov, N. V. Zyk, D. G. Weiss, S. A. Kuznetsov, N. S. Zefirov, “Design, synthesis and bioactivity of simplified taxol analogues on the basis of bicyclo[3.3.1]nonane derivatives”, Mendeleev Commun., 18:4 (2008), 183

Эта публикация цитируется в 22 статьях

Design, synthesis and bioactivity of simplified taxol analogues on the basis of bicyclo[3.3.1]nonane derivatives

O. N. Zefirova^a, E. V. Nurieva^a, H. Lemcke^b, A. A. Ivanov^c, N. V. Zyk^a, D. G. Weiss^b, S. A. Kuznetsov^b, N. S. Zefirov^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Institute of Biological Sciences, Cell Biology and Biosystems Technology, University of Rostock, Rostock, Germany
^c Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation

Аннотация: Four specially designed bicyclo[3.3.1]nonane-based structures were synthesised and found to be cytotoxic at micromolar concentrations and to cause slight non-specific tubulin aggregation.

Язык публикации: английский

DOI: 10.1016/j.mencom.2008.07.003

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