Facile synthesis of cone p-tert-butylcalix[4]arene-crown conformers

The series of p-tert-butylcalix[4]arene-crowns in the cone conformation was synthesised in high yields under conditions producing disubstituted calix[4]arenes in the presence of K₂CO₃ in acetonitrile; the formation of calix-bis(crown)s and doubly(calix)-doubly(crown) in these reactions was established.