A. V. Nemukhin, I. A. Gariev, A. V. Rogov, S. D. Varfolomeev, “Serine hydrolase catalytic sites : geometry invariants and modeling catalytic activity”, Mendeleev Commun., 16:6 (2006), 290

Эта публикация цитируется в 10 статьях

Serine hydrolase catalytic sites : geometry invariants and modeling catalytic activity

A. V. Nemukhin^ab, I. A. Gariev^a, A. V. Rogov^b, S. D. Varfolomeev^ab

^a N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russian Federation
^b Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Аннотация: An analysis of the catalytic site structures and quantum mechanical – molecular mechanical modeling of the reaction mechanism of serine hydrolases provide direct credentials to the Koshland's induced fit concept of enzymatic catalysis.

Язык публикации: английский

DOI: 10.1070/MC2006v016n06ABEH002418