A. S. Efimova, M. A. Ustimova, M. A. Maksimova, A. Yu. Frolova, V. I. Martynov, S. M. Deyev, A. A. Pakhomov, Yu. V. Fedorov, O. A. Fedorova, “Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody”, Mendeleev Commun., 33:3 (2023), 384

Эта публикация цитируется в 6 статьях

Communications

Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody

A. S. Efimova^ab, M. A. Ustimova^a, M. A. Maksimova^acd, A. Yu. Frolova^ac, V. I. Martynov^c, S. M. Deyev^c, A. A. Pakhomov^ac, Yu. V. Fedorov^a, O. A. Fedorova^ab

^a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
^c M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^d Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Аннотация: Two new styryl-type dyes modified with the succinimide ester group were prepared for conjugation with antibodies. The optical characteristics of the obtained compounds in different solvents were studied, and the solvatochromic properties of these dyes were revealed. The applicability of the dyes as protein labels was demonstrated in cyto-fluorometry and fluorescence microscopy.

Ключевые слова: fluorescent probes, covalent labeling, antibody, protein, styryl dyes, pyridinium salts.

Язык публикации: английский

DOI: 10.1016/j.mencom.2023.04.027

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