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ЖУРНАЛЫ // Mendeleev Communications // Архив

Mendeleev Commun., 1997, том 7, выпуск 6, страницы 243–244 (Mi mendc4878)

Эта публикация цитируется в 7 статьях

New oxidative reactions of 1,2,3,6-tetrahydropyridines: imination, lactamination and decyclisation in the presence of potassium permanganate

A. T. Soldatenkov, V. V. Shereshovets, I. A. Bekro, T. P. Khristoforova, S. A. Soldatova, B. N. Anissimov

Peoples Friendship University of Russia (RUDN University), Moscow, Russian Federation

Аннотация: A novel oxidative imination reaction of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 1a by 4-nitroaniline/potassium permanganate has been found to occur yielding 2-(4-nitrophenyl)imino-1,2,5,6-tetrahydropyridine 4; in the absence of nitroaniline the shorter reaction time allows the reaction to be stopped at the unsaturated lactam 5 formation stage; the oxidation of 1a hydrochloride leads to 1-(N-formyl-N-methyl)amino-3-phenylpropan-2-one 6 via decyclisation–elimination steps, providing a new method for N-formyl-substituted aminoketone synthesis.

Язык публикации: английский

DOI: 10.1070/MC1997v007n06ABEH000870



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