Mendeleev Commun.,
1996 , том 6, выпуск 4, страницы 161–163
(Mi mendc4961)
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β-Mercaptoguanidine derivatives – new class of potential NO-generating compounds V. G. Granik a ,
N. B. Grigoriev b ,
L. L. Vinograd b ,
I. S. Severina c ,
M. D. Mashkovskii b ,
V. B. Nikitin b ,
G. N. Engalycheva b ,
M. A. Kalinkina b ,
O. G. Busigina c a Russian Research Centre 'Research Institute of Organic Intermediates and Dyes', Moscow, Russian Federation b Centre for Medicinal Chemistry. Sergo Ordzhonikidze All-Russian Research Chemical-Pharmaceutical Institute, Moscow, Russian Federation c V.N. Orekhovich Institute of Biomedical Chemistry, Moscow, Russian Federation Аннотация:
β-Mercaptoguanidine derivatives generate nitric oxide under oxidation
in vitro and
in vivo , activate soluble guanylate cyclase and diminish arterial blood pressure.
Язык публикации: английский
DOI:
10.1070/MC1996v006n04ABEH000629
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