L-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction

We synthesized a biocompatible substrate of the peroxy-oxalate chemiluminescent reaction on the basis of N-benzoyl-L-tyrosine ethyl ester. Its ability to interact with hydrogen peroxide was evaluated by light emission in the presence of a perylene activator. Its cytotoxicity is three times less than that of bis[2,4,5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate (CPPO).