Communications
3,3,4,4-Tetracyanoalkanones as expedient reagents for utilization of N,N-dimethylhydrazine
O. E. Nasakina,
E. S. Ivanovaa,
M. A. Maryasova,
V. V. Andreevaa,
S. V. Karpova,
O. A. Lodochnikovab,
D. Yu. Grishaevc a Department of Chemistry, I.N. Ulyanov Chuvash State University, Cheboksary, Russian Federation
b A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
c Pharmacy Research & Education Center, Kazan Federal University, Kazan, Russian Federation
Аннотация:
To utilize
N,N-dimethylhydrazine, the corresponding +formaldehyde hydrazone was reacted with 1,1,2,2-tetra-cyanoethane or 3,3,4,4-tetracyanoalkanones. The first process yielded 5-amino-1-dimethylamino-1,2-dihydro-3
H-pyrrole-3,3,4-tricarbonitrile while the second afforded pyrrolo[3,4-
c]quinolone multifunctional derivatives. These resultant products hold promise in molecular design and pharmaceutical chemistry.
Ключевые слова:
N,N-dimethylhydrazine, formaldehyde dimethylhydrazone, tetracyanoethylene, 3,3,4,4-tetracyanoalkanones, Thorpe–Ziegler type cyclization, 1,2-dihydro-3
H-pyrrole-3,3,4-tricarbonitriles, 4,5-dihydro-1
H-pyrrolo[3,4-
c]pyridine-3a,7a-dicarbonitriles.
Язык публикации: английский
DOI:
10.1016/j.mencom.2023.10.039
Полный текст:
PDF файл (219 kB)
