V. E. Filatov, D. A. Iuzabchuk, B. N. Tarasevich, N. V. Zyk, E. K. Beloglazkina, “A convenient E-diastereoselective synthesis of NH-isatin N′-arylimines via the aza-Wittig reaction”, Mendeleev Commun., 32:5 (2022), 634

Communications

A convenient E-diastereoselective synthesis of NH-isatin N′-arylimines via the aza-Wittig reaction

V. E. Filatov, D. A. Iuzabchuk, B. N. Tarasevich, N. V. Zyk, E. K. Beloglazkina

Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Аннотация: A general synthesis of NH-isatin N′-arylimines involves the aza-Wittig reaction of isatin and aryl azides, providing higher E-diastereoselectivity as compared to previously described methods. The procedure is applicable even to anilines which do not directly react with isatins.

Ключевые слова: aryl isatin imines, aryl azides, imines, isatins, aza-Wittig reaction, stereoselectivity.

Язык публикации: английский

DOI: 10.1016/j.mencom.2022.09.022

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