V. A. Shchelkonogov, A. M. Inshakova, A. V. Shipelova, O. A. Baranova, A. V. Chekanov, N. S. Shastina, E. Yu. Solov'eva, A. I. Fedin, “Nanoparticles of lipoic acid esters: preparation and antioxidant effect”, Mendeleev Commun., 31:4 (2021), 507

Эта публикация цитируется в 3 статьях

Communications

Nanoparticles of lipoic acid esters: preparation and antioxidant effect

V. A. Shchelkonogov^ab, A. M. Inshakova^a, A. V. Shipelova^a, O. A. Baranova^b, A. V. Chekanov^b, N. S. Shastina^a, E. Yu. Solov'eva^b, A. I. Fedin^b

^a M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation
^b N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation

Аннотация: Five lipoic acid esters were synthesized, and their nanoforms based on copolymer Pluronic F68 and phosphatidylcholine were obtained. The most pronounced antioxidant effect on neutrophils activated by phorbol-12-myristate-13-acetate was shown by the nanodispersion containing the derivative of lipoic acid with hexane-1,6-diol, reducing the concentration of reactive oxygen species by 7.5 times.

Язык публикации: английский

DOI: 10.1016/j.mencom.2021.07.023

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