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ЖУРНАЛЫ // Mendeleev Communications // Архив

Mendeleev Commun., 2021, том 31, выпуск 4, страницы 507–508 (Mi mendc971)

Эта публикация цитируется в 3 статьях

Communications

Nanoparticles of lipoic acid esters: preparation and antioxidant effect

V. A. Shchelkonogovab, A. M. Inshakovaa, A. V. Shipelovaa, O. A. Baranovab, A. V. Chekanovb, N. S. Shastinaa, E. Yu. Solov'evab, A. I. Fedinb

a M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation
b N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation


Аннотация: Five lipoic acid esters were synthesized, and their nanoforms based on copolymer Pluronic F68 and phosphatidylcholine were obtained. The most pronounced antioxidant effect on neutrophils activated by phorbol-12-myristate-13-acetate was shown by the nanodispersion containing the derivative of lipoic acid with hexane-1,6-diol, reducing the concentration of reactive oxygen species by 7.5 times.

Язык публикации: английский

DOI: 10.1016/j.mencom.2021.07.023



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